THE DIFFERENCE IN THE IMPACT OF INTERFERENCES ON RESULT ACCURACY BEFORE AND AFTER THE APPLICATION OF THE HIL INDEX

 XXI međunarodna konvencija o kvalitetu JUSK ICQ – 29 – 31. maj 2025, Beograd, (172-178 str.)

 

АУТОР(И) / AUTHOR(S): Jelena Marjanović 

 

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DOI:  10.46793/XXIJUSK-ICQ.172M

САЖЕТАК / ABSTRACT:

Interferences such as hemolysis, icterus, and lipemia are relatively common in routine laboratory practice and can significantly affect the accuracy and precision of laboratory test results. Early detection and minimization of these interferences are essential for improving the quality and reliability of laboratory testing. One method for identifying interference is visual assessment, which is quick and cost-effective but inherently subjective and insufficiently accurate. In contrast, automated interference index measurement allows for faster and more precise identification of interferents in serum or plasma. Interference indices are used to generate both qualitative and quantitative assessments of the presence of hemolysis, icterus, or lipemia, enabling more reliable interpretation of interferences. This method supports laboratory personnel in making informed decisions regarding the handling of affected samples. Subsequent steps may include sample recollection, with holding of results affected by interference, or releasing results accompanied by an interpretative comment regarding the presence of interference and its potential impact on result accuracy.

КЉУЧНЕ РЕЧИ / KEYWORDS:

interference, hemolysis, icterus, lipemia, interference index, precision, accuracy

ПРОЈЕКАТ / ACKNOWLEDGEMENT:

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