COMPARATIVE STUDY OF TIO2 AND SURFACE-MODIFIED TIO2 ON REDOX AND LIPID PARAMETERS IN HUMAN FIBROBLAST CELLS

17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings, Volume II) (2024) [S-06-P, pp. 735-738]   

AUTHOR(S) / АУТОР(И): Jadranka Miletić Vukajlović , Katarina Bobić , Jelena Filipović Tričković , Ana Valenta Šobot , Jelena Martinović , Ivana Guševac Stojanović and Snežana Pejić

Download Full Pdf 

DOI: 10.46793/Phys.Chem24II.735MV

ABSTRACT / САЖЕТАК:

Titanium dioxide nanoparticles (TiO2 NPs) find widespread application in both industrial and consumer goods, encompassing sectors such as cosmetics, pharmaceuticals, food and beverages, and more. This study investigated redox state parameters and lipid peroxidation parameter in human fibroblast cells treated with different concentrations of NPs. The NPs used included bare TiO2 and TiO2 modified with salicylic acid (SA). The parameter values were compared both with the control group and among the treated groups. Obtained results showed that all investigated NPs promoted oxidative stress in human fibroblast cells.

KEYWORDS / КЉУЧНЕ РЕЧИ:

ACKNOWLEDGEMENT / ПРОЈЕКАТ:

This work was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (grant no 451-03-66/2024-03/200017).

REFERENCES / ЛИТЕРАТУРА:

  • S. Shabbir, MF. Kulyar, ZA. Bhutta, P. Boruah, M. Asif, BioNanoScience. 11 (2021) 621.
  • JC Lai, MB Lai, Jandhyam, VV Dukhande, A. Bhushan, CK Daniels, SW Leung, Int J Nanomedicine 3 (2008) 533.
  • AB da Silva, Miniter, W. Thom, RE Hewitt, J. Wills, R. Jugdaohsingh, JJ. Powell, Curr. Opin. Toxicol. 19 (2020) 112.
  • S. Murugadoss, F. Brassinne, N. Sebaihi, J. Petry, SM. Cokic, KL.Van Landuyt, L. Godderis, J. Mast, D. Lison, PH. Hoet, S. Van Den Brûle, Part fibre toxicol. (2020) 1.
  • J. Wang, G. Zhou, C. Chen, H. Yu, T. Wang, Y. Ma, G. Jia., Y. Gao, B. Li, J. Sun, Y. Li, F. Jiao, Zhao, Z. Chai, Toxicol. Lett. 68 (2007a.) 176.
  • K. B. Li, X.Z. Li, Chemosphere 48 (2002) 1103.
  • S. K. Zheng, T.M. Wang, W.C. Hao, R. Shen, Vacuum 65 (2002) 155.
  • A. P. Xagas, M.C. Bernard, A.H.L. Goff, N. Spyrellis, Z. Loizos, P. Falaras, J. Photochem. Photobiol. A: Chem. 132 (2000) 115.
  • S. H. Bossmann, S. Gob, T.B. Siegenthaler, M. Andre, K.T. Ranjit, I. Willner, Fresenius J. Anal. Chem. 371 (2001) 621.
  • S. Đurašević, G. Nikolić, A. Todorović, D. Drakulić, S. Pejić, V. Martinović, D. Mitić-Ćulafić, Milić, T. J. Kop, N. Jasnić, J. Đorđević, and Z. Todorović, Food Chem. Toxicol., 140 (2020) 111302.
  • Y. Cheng-Yu, Z. Bang-Shang, W. Xue-Feng, L. Qing-Hua, Chem. Res. Toxicol. 21 (2008) 1871.
  • Y. Ze, L. Zheng, X. Zhao, S. Gui, X. Sang, J. Su, N. Guan, L. Zhu, L. Sheng, R. Hu, and J. Cheng. Chemosphere, 92 (2013) 1183.
  • Z. Pan, W. Lee, L. Slutsky, RA. Clark,|N. Pernodet, MH. Rafailovich, Small. 5 (2009) 511.