17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings, Volume II) (2024) [O-18-P, pp. 655-658]
AUTHOR(S) / AUTOR(I): Kristina Stevanović 
, Sanja Glišić and Milan Senćanski
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DOI: 10.46793/Phys.Chem24II.655S
ABSTRACT / SAŽETAK:
γ-Aminobutyric acid (GABA) targets are relevant in drug discovery because modulation of its levels can be used in the treatment of various diseases, such as epilepsy, anxiety and depression. Using a combined in silico approach, we focused on GABA transporter 1 to select new inhibitors from the ZINC database. A set of known inhibitors was used as a reference. Our results propose several compounds as potential new ligands.
KEYWORDS / KLJUČNE REČI:
ACKNOWLEDGEMENT / PROJEKAT:
This work was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (grant no 451-03-66/2024-03/200017).
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