17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings, Volume I) (2024) [H-08-P, pp. 305-308]
AUTHOR(S) / АУТОР(И): Zorana Rogić Miladinović 
, Maja Krstić , Georgi Stamboliev , Edin Suljovrujić
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DOI: 10.46793/Phys.Chem24I.305M
ABSTRACT / САЖЕТАК:
This study investigates the thermal properties of methacrylate hydrogels modified with short ethylene glycol (EG) and propylene glycol (PG) pendant chains, synthesized via radiation-induced crosslinking and polymerization. The hydrogels were characterized through swelling behavior and differential scanning calorimetry (DSC) measurements to determine volume phase transition temperatures (VPTT). While polymeric systems with EG chains exhibit high biocompatibility with a VPTT exceeding physiological levels, systems with PG chains display thermosensitivity below 13 °C due to their hydrophobic nature. To obtain hydrogels with VPTT around physiological temperatures, hydrogels with both EG and PG pendant chains, which have a predetermined ratio of EG and PG units within the methacrylate hydrogel backbone, were synthesized. Our findings highlight the influence of EG and PG compositions on the temperature-responsive behavior of hydrogels, crucial for biomedical applications.
KEYWORDS / КЉУЧНЕ РЕЧИ:
ACKNOWLEDGEMENT / ПРОЈЕКАТ:
The research was funded by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (No. 451-03-66/2024-03/ 200017).
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