17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings, Volume I) (2024) [D-04-SL, pp. 139-141]
AUTHOR(S) / АУТОР(И): Katarina Novakovic 
, E. Hutchinson, Wing Man Lau , T. Abdelghany and Keng Wooi Ng
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DOI: 10.46793/Phys.Chem24I.139N
ABSTRACT / САЖЕТАК:
Microneedle patches, with needles of sub-millimeter size, are non-invasive and pain free way of drug delivery. The needles penetrate skin, pass stratum corneum, but do not penetrate tissue which contains nerves and blood vessels. In this work, a new and unique chitosan-hydrogel based composite material was formulated to produce microneedle patches and their potency for extended drug delivery was validated using methylene blue as a model drug.
KEYWORDS / КЉУЧНЕ РЕЧИ:
ACKNOWLEDGEMENT / ПРОЈЕКАТ:
This work was supported by the EPSRC IAA, Northern Accelerator, Newcastle University HEIF funding, and Innovate UK ICURe funding.
REFERENCES / ЛИТЕРАТУРА:
- R. F. Donnelly, T. R. R. Singh, M.J. Garland, K. Migalska, R. Majithiya, C. M. McCrudden, P. Kole, T. M. T. Mahmood, H. O. McCarthy, A. D. Woolfson, Advanced Functional Materials, 22 (2012) 4879.
- J, G. Turner, L. R. White, P. Estrela, H. S. Leese, Macromolecular Bioscience, 21 (2021) 2000307.
- E. Smith, W. M. Lau, T. M. Abdelghany, Dj. Vukajlovic, K. Novakovic, K. W. Ng, International Journal of Pharmaceutics, 650 (2024) 123706.