17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings,Volume I) (2024) [PL-01, pp. 003]
AUTHOR(S) / АУТОР(И): Leonard J. Prins 
Download Full Pdf 
DOI: 10.46793/Phys.Chem24I.003P
ABSTRACT / САЖЕТАК:
The development of synthetic active matter requires the ability to rationally design materials capable of harnessing energy from a source to carry out work.[1,2] Nature achieves this using metabolic cycles in which energy released from an exergonic chemical reaction, e.g. ATP hydrolysis, is used to drive endergonic biochemical processes. Extensive theoretical and experimental studies on synthetic molecular machinery have demonstrated that energy and information ratchet mechanisms play an essential role in transferring energy from the energy source to the system.[3, 4] Recently, it has been understood that these mechanisms can also be exploited for the development of active matter [5, 6]. Here, we report our progress made on the use of energy and information ratchet mechanisms for the synthesis of high-energy molecular structures [8, 9].
In daily clinical practice, it is necessary to clearly specify the goals of treatment with diuretics, to evaluate the effectiveness of their application, to solve the problems of diuretic resistance and to use the advantages of diuretic synergism
KEYWORDS / КЉУЧНЕ РЕЧИ:
ACKNOWLEDGEMENT / ПРОЈЕКАТ:
Funding from MUR (2022TSB8P7 and P2022ANCEK) and the University of Padova (P-DiSC #CASA-BIRD2022-UNIPD) is acknowledged.
REFERENCES / ЛИТЕРАТУРА:
- Cheng, P.R. McGonigal, J.F. Stoddart, R.D. Astumian, ACS Nano 9 (2015) 8672–8688.
- Walther, Adv. Mater. 32 (2020) 1–10.
- E.R. Kay, D.A. Leigh, F. Zerbetto, Chem. Int. Ed., 46 (2007) 72-191.
- Feng, M. Ovalle, J.S.W. Seale, C.K. Lee, D.J. Kim, R.D. Astumian, J.F. Stoddart, J. Am. Chem. Soc., 143 (2021) 5569–5591.
- Ragazzon, L.J. Prins, Nat. Nanotechnol., 13 (2018) 882–889.
- Das, L. Gabrielli, L.J. Prins, Angew. Chem. Int. Ed., 60 (2021) 20120-20143.
- Marchetti, D. Frezzato, L. Gabrielli, L.J. Prins, Angew.Chem.Int.Ed. 2023, e202307530
- (+) T. Marchetti, (+) B.W.M. Roberts, D. Frezzato, L.J. Prins, Angew.Chem.Int.Ed 2024, e202402965. (+) both authors contributed equally.