8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, ( pp. 1–8)
АУТОР / AUTHOR(S): N. Dreolin 
, S. Adams, K. L. Organtini, S. Hird, O. Burt and C. Rathmann
DOI: 10.46793/8FDSQ.PLA1ND
САЖЕТАК / ABSTRACT:
This study introduces an optimized LC-MS/MS methodology for the comprehensive analysis of Per- and Polyfluoroalkyl Substances (PFAS) in vegetable, fruit, and baby food. The method demonstrates an exceptionally low limit of quantification, reaching 0.0005 µg/kg for some compounds in matrix, while accurately detecting and quantifying the PFAS compounds listed in the Commission Recommendation (EU) 2022/1431. The combination of enhanced sensitivity of the Xevo™ TQ Absolute MS System, with the increased clean-up efficacy of a prototype bilayer dual-phase GCB/WAX SPE cartridge, gave excellent recoveries, between 87 and 116% for the mandatory PFAS, and between 65 and 131% for the majority of the recommended compounds along with repeatability (RSDr) ≤10%.
КЉУЧНЕ РЕЧИ / KEYWORDS:
ЛИТЕРАТУРА / REFERENCES:
[1] Commission Regulation (EU) 2022/2388, amending Regulation (EC) No 1881/2006 as regards maximum levels of perfluoroalkyl substances in certain foodstuffs, L 316/38, 2022.
[2] Commission Recommendation (EU) 2022/1431, on the monitoring of perfluoroalkyl substances in food. L 221/105, 2022.
[3] Commission Implementing Regulation (EU) 2022/1428, L 221/66, 2022.
[4] EURL for halogenated POPs in feed and food (2022): Guidance Document on Analytical Parameters for the Determination of Per- and Polyfluoroalkyl Substances (PFAS) in Food and Feed, version 1.2 of 11 May 2022.
[5] N. Dreolin, H. Foddy, K. Organtini, S. Adams, K. Rosnack, P. Hancock, Waters White Paper. 720007905, 2023.
[6] S. Adams, N. Dreolin, K. Organtini, P. Hancock, Waters Application Note. 720008108, 2023.
[7] B. Magnusson and U. Örnemark (eds.) Eurachem Guide: (2nd ed. 2014). ISBN 978-91-87461-59-0.