8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, (pp. 206–209)
АУТОР / AUTHOR(S): J. Miletić Vukajlović 
, A. Todorović , F. Veljković , K. Bobić , J. Martinović , I. Guševac Stojanović , D. Drakulić
DOI: 10.46793/8FDSQ.PD7MV
САЖЕТАК / ABSTRACT:
Although the use of flaxseed oil that is rich with essential nutrients, has been associated with health benefits, robust scientific evidence supporting its efficacy is currently lacking. In this study, we evaluated the impact of chronic intragastric treatment of commercially available flaxseed oil by assessing several parameters of oxidative stress including pro/antioxidant balance (PAB), levels of lipid peroxidation (LPO) products and advanced oxidation protein products (AOPP) as well as activity of total superoxide dismutase (totSOD) in rat stomach. Obtained results indicate that treatment maintains the general prooxidant load and antioxidant capacity, as evidenced by the unchanged PAB levels. However, it notably elevated LPO products and AOPP levels along with totSOD activity suggesting that increased oxidative changes of lipids and proteins might be attenuated by antioxidant system.
КЉУЧНЕ РЕЧИ / KEYWORDS:
ПРОЈЕКАТ / ACKNOWLEDGEMENT:
This work was supported by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (Grant no. 451-03-66/2024-03/200017).
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