8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, (pp.202–205)
АУТОР / AUTHOR(S): A. Leskovac 
, B. Laban , T. Momić , S. Petrović
DOI: 10.46793/8FDSQ.PC6AL
САЖЕТАК / ABSTRACT:
This study aimed to evaluate the protective effects of curcumin on cellular redox homeostasis and its impact on reactive oxygen species (ROS)- related genotoxicity in vitro. The cytokinesis-block micronucleus (CBMN) test assessed genotoxicity, while thiobarbituric acid reactive substances (TBARS) levels measured oxidative stress induction using standard spectrophotometric methods. Results demonstrate that curcumin exhibited significant protective effects across all concentrations tested, highlighting its potential to maintain cellular homeostasis and mitigate oxidative damage.
КЉУЧНЕ РЕЧИ / KEYWORDS:
ПРОЈЕКАТ / ACKNOWLEDGEMENT:
This work was supported by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (Grant no. 451-03-66/2024-03/200017).
ЛИТЕРАТУРА / REFERENCES:
[1] J. Nuszkiewicz, A.Woźniak, K. Szewczyk-Golec, Int. J. Mol. Sci., 2020, 21(16).
[2] M. Zivkovic Radojevic, N. Milosavljevic, T.B. Miladinovic, S. Jankovic, M. Folic, Int. J. Radiat. Biol.. 2023, 99(4), 594-603.
[3] Y. Cihan, Klin. Onkol., 2021, 34, 273-277.
[4] Law on Health Care Official Gazette of the Republic of Serbia, no. 25/2019.
[5] M. Fenech, Mutat. Res., 1993, 285, 35-44.
[6] J. Surralles, N. Xamena, A. Creus, R. Marcos, Mutat. Res., 1995, 342, 43-59.
[7] O. I. Aruoma, B. Halliwell, M.J. Laughton, G.J. Quinlan., J.M.C. Gutteridge, Biochem. J., 1989, 258, 617-620.