8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, (pp.163–166)
АУТОР / AUTHOR(S): M. B. Živković 
, S. J. Tufegdžić , I. T. Novaković , S. B. Šegan , D. M. Sladić
DOI: 10.46793/8FDSQ.PC8MZ
САЖЕТАК / ABSTRACT:
Anti-DPPH activity and in silico lipophilicity of six steroidal semi- and thiosemicarbazones were determined. As expected, sulfur derivatives exhibited higher activity than oxygen analogues. Lipophilicity determined by the shake-flask method (logP=4.5±0.2) for androstane thiosemicarbazone with the best antioxidative activity of 0.298 mM was in good agreement with the value obtained by calculation using the Chemaxon calculator (logP=4.62).
КЉУЧНЕ РЕЧИ / KEYWORDS:
ПРОЈЕКАТ / ACKNOWLEDGEMENT:
This work was supported by the Ministry of Science, Technological Development and Innovation of the Republic of Serbia (Grant no. 451-03-66/2024-03/200026).
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