RADICAL SCAVENGING POTENTIAL OF DIFFERENT TYPES OF LIPOSOME PARTICLES WITH ENCAPSULATED CAROB EXTRACT

8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, (pp. 25–28)

 

АУТОР / AUTHOR(S): D. Dekanski , A. Rašković ,  N. Martić , A. Pirković , A. Jovanović

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DOI: 10.46793/8FDSQ.PA3DD

САЖЕТАК / ABSTRACT:

Carob pulp extract contains bioactive phenolic compounds, making it a suitable functional food ingredient. This study aimed to investigate the radical scavenging potential of pure carob extract and different types of carob extract-loaded liposomes (multilamellar, UV-irradiated, and sonicated unilamellar vesicles). Their antioxidant capacity was measured by employing DPPH and ABTS assays. The encapsulation of carob extract within liposomes as well as UV irradiation and sonication did not cause a decrease in the anti-DPPH activity, however, the ABTS radical scavenging potential of pure extract was significantly lower compared to encapsulated counterparts. UV irradiation and sonication significantly decreased the anti-ABTS effect of the liposome with the extract. Carob pulp extract and its liposomal formulations displayed significant in vitro antioxidant potential that can be of interest for further development as a functional food ingredient or in the prevention/treatment of various diseases.

КЉУЧНЕ РЕЧИ / KEYWORDS:

ПРОЈЕКАТ/ ACKNOWLEDGEMENT:

This work was supported by the Ministry of Science, Technological Development and Innovation, Republic of Serbia (No. 451-03-66/2024-03/200019 and by the Provincial Secretariat for Higher Education and Scientific Research of Vojvodina (No. 142-451-3531/2023-01). The authors express gratitude to Z. Šereš, D. Šoronja-Simović, and J. Zahorec for extract preparation.

ЛИТЕРАТУРА / REFERENCES: 

[1] W. Dahmani, N. Elaouni, A. Abousalim, Z. L. E. Akissi, A. Legssyer, A. Ziyyat, S. Sahpaz, Plants (Basel), 2023, 12(18), 3303.

[2] J. Zahorec, D. Šoronja-Simović, S. Kocić-Tanackov, S. Bulut, N. Martić, K. Bijelić, D. Božović, B. Pavlić, Separations, 2023, 10(9), 465.

[3] A. A. Jovanović, B. Balanč, M. Volić, I. Pećinar, J. Živković, K. Šavikin, Plants, 2023, 12, 3063.

[4] A. Jovanović, B. Balanč, A. Ota, A. Pegi, V. Djordjević, K. Šavikin, B. Bugarski, V. Nedović, N. Poklar-Ulrih, European Journal of Lipid Science and Technology, 2018, 120, 1–41.

[5] P. Batinić, N. Čutović, S. Mrđan, A. Jovanović, K. Čirić, A. Marinković, B. Bugarski, Lekovite Sirovine, 2022, 42(1), 43–50.

[6] P. Petrović, K. Ivanović, C. Octrue, M. Tumara, A. Jovanović, J. Vunduk, M. Nikšić, R. Pjanović, B. Bugarski, A. Klaus, Hemijska Industrija, 2019, 73(5), 325–335.

[7] A. Dammak, F. Chtourou, S. V. Luca, K. Skalicka-Wozniak, M. Bouaziz, Fitoterapia, 2024, 75, 105919.