17th International Conference on Fundamental and Applied Aspects of Physical Chemistry (Proceedings, Volume I) (2024) [H-27-P, pp. 381-384]
AUTHOR(S) / АУТОР(И): Đorđe Antonijević 
, Ana Despotović , Veljko Ilić , Dejan Ćetković , Aleksandra Dožić , Kristina Janjetović , Nevena Zogović and Sanja Milutinović-Smiljanić
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DOI: 10.46793/Phys.Chem24I.381A
ABSTRACT / САЖЕТАК:
This study investigates the wettability and biocompatibility of different magnesium silicate-based dental cements. Experimental cements (EC1, EC2, and EC3) were composed of magnesium silicate, calcium silicate, calcium aluminate, strontium carbonate, and zirconium oxide, in different ratios. MTA (Cerkamed) was used as a control. Wettability was investigated using a contact angle analyzer, while morphology and proliferation of L929 murine fibroblast cells were used for assessment of biocompatibility. The contact angle between human plasma and EC2 was the lowest, while the highest was observed for MTA. MTA slightly slowed cell proliferation, whereas EC1, EC2, and EC3, exposed a strong influence on proliferation capacity and cell morphology, and no effect on cell viability, suggesting that cell differentiation may be initiated. These results advocate that proposed dental cements based on magnesium silicate may be a suitable alternative to commercially available calcium silicate cements.
KEYWORDS / КЉУЧНЕ РЕЧИ:
ACKNOWLEDGEMENT / ПРОЈЕКАТ:
This study was supported by the Ministry of Science, Technological Development and Innovation (Grant No. 451-03-66/2024-03/200007) and by a bilateral PPP grant provided jointly by the Ministry of Education, Science and Technological Development of the Republic of Serbia and Ministry of Science and Technology of The People’s Republic of China (Grant No. 451-02- 818/2021-09/20).
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