8th WORKSHOP: FOOD AND DRUG SAFETY AND QUALITY, (pp. 210–213)
АУТОР / AUTHOR(S): A. Pirković 
, D. Dekanski , M. Hadži-Mihailović , D. Stanimirović , M. Prokić , Ž. Bojić-Trbojević
DOI: 10.46793/8FDSQ.PD8AP
САЖЕТАК / ABSTRACT:
The oxidative stress has a role in etiopathogenesis of oral lichen planus (OLP). Polyphenols renowned for their antioxidative, anti-inflammatory and immunomodulatory properties, have gained attention in autoimmune diseases management. Saliva, reflecting salivary gland health, offers promise for biomarker research and treatment monitoring. The aim of this study was to evaluate salivary levels of reactive oxygen species (ROS) in OLP patients using polyphenol rich, standardized Aronia melanocarpa extract (SAE). The ROS values were compared in pre- and post-treatment and significant differences were found, indicating the decrease of ROS after four-week supplementation with SAE.
КЉУЧНЕ РЕЧИ / KEYWORDS:
ПРОЈЕКАТ/ ACKNOWLEDGEMENT:
This work was supported by the Ministry of Science, Technological Development and Innovation, Republic of Serbia (Grant No. 451-03-66/2024-03/200019).
ЛИТЕРАТУРА / REFERENCES:
[1] B. Vahapoglu, E. Erskine, B. Gultekin Subasi, E. Capanoglu, Molecules, 2021, 27(1), 108.
[2] J. Oszmiański, A. Wojdylo, European Food Research and Technology, 2005, 221,809-813.
[3] Y. Ren, T. Frank, G. Meyer, J. Lei, J. R. Grebenc, R. Slaughter, Y. G. Gao, A. D. Kinghorn, Molecules, 2022, 27(22), 7823.
[4] T. Jurendić, M. Ščetar.N. Antioxidants (Basel), 2021, 10(7), 1052.
[5] S. Singh, J. Singh, B. C. Biradar, M. Sonam, S. Chandra, F. M. Samadi, Journal of Oral and Maxillofacial Pathology, 2022, 26(1), 26-30.
[6] N. Cikiriz, I. Milosavljevic, B. Jakovljevic, S. Bolevich, J. Jeremic, T. Nikolic Turnic, M. Mitrovic, I. Srejovic, S. Bolevich, V. Jakovljevic. Canadian Journal of Physiology and Pharmacology, 2021, 99(1), 42-47.
[7] N. Tasic, V. LJ. Jakovljevic, M. Mitrovic, B. Djindjic, D. Tasic, D. Dragisic, Z. Citakovic, Z. Kovacevic, K. Radoman, V. Zivkovic, S. Bolevich, T. N. Turnic, Molecular and Cellular Biochemistry, 2021, 476(7), 2663-2673.