Chemia Naissensis Volume 3, No.2 (2020) (стр. 89-99)
АУТОР(И) / AUTHOR(S): Jovana D. Ickovski, Milan N. Mitić, Milan B. Stojković, Gordana S. Stojanović
Е-АДРЕСА / E-MAIL: jovana.ickovski@pmf.edu.rs
DOI: 10.46793/ChemN3.2.089I
САЖЕТАК / ABSTRACT:
Artemisia alba Turra was collected at the blooming stage on two different locations in Serbia, Mojinci and Rosomač. Antioxidant activity and HPLC profiles of their methanolic extracts were determined and compared. Flavonoid compounds found in both samples were rutin, apigenin glucoside, quercetin, luteolin, kaempferol and apigenin, while detected phenolic acids were chlorogenic acid, p-coumaric acid, cynarine and rosmarinic acid. The only observed qualitative difference was related to the presence of vanillic acid. Extract of A. alba from Rosomač was richer in phenolic compounds and flavonoids than A. alba from Mojinci. The extract of A. alba from Rosomač also possessed higher antioxidant capacity than A. alba from Mojinci, which was especially noticed in the 2,2-diphenyl-1-picrylhydrazyl assay. Only the results for the ferric ion reducing antioxidant power assay were higher for extract of A. alba from Mojinci, than for the extract of A. alba from Rosomač.
КЉУЧНЕ РЕЧИ / KEYWORDS:
Artemisia alba, methanolic extract, HPLC, antioxidant activity
ЛИТЕРАТУРА / REFERENCES:
- Apak, R., Güçlü, K., Özyürek, M., & Karademir, S. E. (2004). Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method. Journal of Agricultural and Food Chemistry, 52, 7970-7981.
- Benzie, I. F. F., & Strain, J. J. (1996). The ferric reducing ability of plasma (FRAP) as a measure of “Antioxidant Power”: The FRAP assay. Analytical Biochemistry, 239, 70-76.
- Bora, S., & Sharma, A. (2011). The genus Artemisia: A comprehensive review. Pharmaceutical Biology, 49, 101-109.
- Đorđević, , Stanisavljević, D., Ristić, M., Milenković, M., Veličković, D., Stojičević, S., & Zlatković, B. (2013). Chemical, antioxidant and antimicrobial analysis of the essential oil and extract of Artemisia alba Turra. Digest Journal of Nanomaterials & Biostructures, 8, 1377-1388.
- Fraisse, D., Felgines, C., Texier, O., & Lamaison, J. L. (2011). Caffeoyl derivatives: major antioxidant compounds of some wild herbs of the Asteraceae family. Food and Nutrition Sciences, 2, 181-192.
- Guarrera, P. M. (2005). Traditional phytotherapy in Central Italy (Marche, Abruzzo, and Latium). Fitoterapia, 76, 1-25.
- Hatano, T., Kagawa, H., Yasuhara, T., & Okuda, T. (1988). Two new flavonoids and other constituents in licorice root: their relative astringency and radical scavenging effects. Chemical and Pharmaceutical Bulletin, 36, 2090-2097.
- Mitić, M. N., Obradović, M. V., Mitić, S. S., Pavlović, A. N., Pavlović, J. LJ., & Stojanović, B. T. (2013). Free radical scavenging activity and phenolic profile of selected Serbian red fruit Revista de Chimie, 64, 68-73.
- Nikolova, M., Gussev, Ch., & Nguyen, T. (2010). Evaluation of the antioxidant action and flavonoid composition of Artemisia species extracts. Biotechnology & Biotechnological Equipment, 24, 101-103.
- Oberprieler, C., Himmelreich, S., & Vogt, R. (2007). A new subtribal classification of the tribe Anthemideae (Compositae). Willdenowia, 37, 89-114.
- Oyaizu, M. (1986). Studies on products of browning reaction. Antioxidative activities of products of browning reaction prepared from glucosamine. Japanese Journal of Nutrition, 44, 307-314.
- Peron, G., Baldan, V., Sut, S., Faggian, M., Roccabruna, L., Zanini, D., Manzini, P., Maggi, F., & Dall’Acqua, (2017). Phytochemical investigations on Artemisia alba Turra growing in the North-East of Italy. Natural Product Research, 31, 1861-1868.
- Radović Jakovljević, , Grujičić, D., Tubić Vukajlović, J., Marković, A., Milutinović, M., Stanković, M., Vuković, N., Vukić, M., Milošević-Đorđević, O. (2020). In vitro study of genotoxic and cytotoxic activities
- of methanol extracts of Artemisia vulgaris and Artemisia alba Turra. South African Journal of Botany, 132, 117-126.
- Radulović, N., & Blagojević, P. (2010). Volatile profiles of Artemisia alba Turra from contrasting serpentine and calcareous habitats. Natural Product Communications, 5, 1117-1122.
- Re, R., Pellegrini, N., Proreggente, A., Pannala, A., Yang, M., & Rice-Evans, C. (1999). Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26, 1231-1237.
- Singleton,V. L., Orthofer, R., & Lamuela-Raventós, R. M. (1999). Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. Methods in Enzymology, 299, 152-178.
- Stojanović, G., Palić, R., & Mitrović, J. (2000). Chemical composition and antimicrobial activity of the essential oil of Artemisia lobelii Journal of Essential Oil Research, 12, 621-624.
- Trendafilova, A., Todorova, M., Genova, V., Peter, S., Wolfram, E., Danova, K., & Evstatieva, L. (2018). Phenolic profile of Artemisia alba Chemistry & Biodiversity, 15, 1872-1880.
- Vajs, V., Trifunović, S., Janaćković, P., Soković, M., Milosavljević, S., & Tešević, V. (2004). Antifungal activity of davanone-type sesquiterpenes from Artemisia lobelii conescens. Journal of the Serbian Chemical Society, 69, 969-972.
- Willcox, M. (2009). Artemisia species: from traditional medicines to modern antimalarial and back again. The Journal of Alternative and Complementary Medicine, 15, 101-109.
- Zhishen, , Mengecheng, T., & Jianming, W. (1999). The determination of flavonoid contents on mulberry and their scavenging effects on superoxide radical. Food Chemistry, 64, 555-559.