1st International Symposium On Biotechnology (2023), [551-555]
AUTHOR(S) / АУТОР(И): Alexandr D. Lukyanov, Danila Y. Donskoy, Miroslav A. Vernezi, Maria S. Mazanko, Tatiana S. Onoyko
E-MAIL: alexlukjanov1998@gmail.com
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DOI: 10.46793/SBT28.551L
ABSTRACT / САЖЕТАК:
In vivo modeling of digestive processes is not a standard mathematical modeling task, taking advanced technologies of several sciences. This article will consider a microbiological complex for modeling the processes occurring in the gastrointestinal tract of animals. The system belongs to mini-models with a working volume of up to 400 ml, the simulation of the dynamics of the mixing of the chyme is static, which significantly simplifies the methodology of conducting experiments, but imposes difficulties on the stages of pretreatment of food matrices. The following characteristics are achieved: reactor volume from 50 to 100 mL; a pH accuracy of ± 0.1; temperature accuracy of ± 0.063 °C.
KEYWORDS / КЉУЧНЕ РЕЧИ:
modeling, microbiological complex, mini-model, in vitro
REFERENCES / ЛИТЕРАТУРА:
- Alegría A., Garcia-Llatas G., Cilla A. (2015). Static Digestion Models: General Introduction. Published in The Impact of Food Bioactives on Health: in vitro and ex vivo models, Verhoeckx K., Cotter P., López-Expósito I., Kleiveland, C., Mackie T.L.A., Requena T., Swiatecka S., Wichers, H. (eds.), pp. 3 – 13 Springer Cham Heidelberg New York Dordrecht London, France & Netherlands.
- Chistyakov V, Lukyanov A., Chapek S., Donskoy D., Katin O. (2020). Modeling and analysis of energy efficiency of methods for maintaining temperature conditions in microbioreactors. IOP Conference Series: Materials Science and Engineering, 012015.
- Mackie A., Rigby N., Macierzanka A., Bajka (2015). Approaches to Static Digestion Models. Published in The Impact of Food Bio-Actives on Gut Health, Verhoeckx K., Cotter P., López-Expósito I., Kleiveland, C., Mackie T.L.A., Requena T., Swiatecka S., Wichers, H. (eds.), pp. 23 – 13 Springer Cham Heidelberg New York Dordrecht London, France & Netherlands