3rd International Conference on Chemo and BioInformatics, Kragujevac, September 25-26. 2025. (pp. 636-639)
АУТОР(И) / AUTHOR(S): Petar B. Stanić, Biljana M. Šmit
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DOI: 10.46793/ICCBIKG25.636S
САЖЕТАК / ABSTRACT:
The aim of this study is the in silico prediction and comprehensive analysis of the pharmacological profile of a mini series of angular triquinane type hydantoin compounds. The ADMET analysis estimates favorable absorption and distribution capabilities. Slow clearance is predicted, so they would have enough time to exhibit their activities. Toxicological assessments predicts the possibility of some toxic effects, so an experimental toxicological evaluation is needed for confirmation. These results could provide a framework for the design, structural optimization and development of novel triquinane hydantoin based therapeutics.
КЉУЧНЕ РЕЧИ / KEYWORDS:
hydantoin, triquinane, alkaloid, ADMET
ПРОЈЕКАТ / ACKNOWLEDGEMENT:
This research is funded by the Ministry of Education and Ministry of Science, Technological Development and Innovation, Republic of Serbia, Grant No. 451-03- 136/2025-03/200378.
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