Chemia Naissensis Volume 1, No.1 (2018) (стр. 187-197)
АУТОР(И) / AUTHOR(S): Lazar N. Kulašević
Е-АДРЕСА / E-MAIL: lazar.kulasevic@gmail.com
DOI: 10.46793/ChemN1.1.187K
САЖЕТАК / ABSTRACT:
Alginate is a natural polysaccharide extracted from the cell walls of brown algae. Thanks to its biocompatibility, biodegradability, nontoxicity, and low cost, this biopolymer is widely applicable across various fields of biomedical science and bioengineering. Alginates are used as a gelling agent in food industry. Alginate hydrogels are an appealing scaffold material because of their resemblance with natural tissues. Consequently, alginates are widely used in tissue engineering and alginate gel beads as transport vehicles in drug delivery systems. Nonetheless, alginate hydrogels are used in nanotechnology to build artificial capillary blood vessels.
КЉУЧНЕ РЕЧИ / KEYWORDS:
alginate, biopolymer, hydrogel, gel beads, drug delivery, tissue engineering
ЛИТЕРАТУРА / REFERENCES:
- Balać et al. (2010). Biomaterijali. Belgrade: Institute of Technical Sciences of SASA, 660– 662.
- Brownlee, I. , Seal, C. J., Wilcox, M., Dettmar, P. W., & Pearson, J. P. (2009). Applications of Alginates in Food. In: Rehm B. (Eds.), Alginates: Biology and Applications. Microbiology Monographs, vol 13. Berlin, Heidelberg: Springer.
- Deepthi, S., & Jayakumar, R. (2017). Alginate nanobeads interspersed fibrin network as in situ forming hydrogel for soft tissue engineering. Bioactive Materials, 3(2), 194–200.
- Draget, K. I., & Taylor, C. (2011). Chemical, physical and biological properties of alginates and their biomedical implications. Food Hydrocolloids, 25, 251–256.
- Draget, K. I., Skjåk-Bræk, G., & Smidsrød, O. (1997). Alginate based new materials. International Journal of Biological Macromolecules, 21, 47–55.
- Drury, J. L., & Mooney, D. J. (2003). Hydrogels for tissue engineering: scaffold design variables and applications. Biomaterials, 24, 4337–4351.
- Gambotz, W. R., & Wee, S. F. (1998). Protein release from alginate matrices. Advanced Drug Delivery Reviews, 31, 267–285.
- George, M., & Abraham, E. (2006). Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan – a review. Journal of Controlled Release, 114, 1–14.
- Henmi, C., Nakamura, M., Nishiyama, Y., Yamaguchi, K., Mochizuki, S., Takiura, K. & Nakagawa, H. (2007). Development of an effective three dimensional fabrication technique using inkjet technology for tissue model Proceedings 6th World Congress on Alternatives & Animal Use in the Life Sciences, 14, 689–692.
- Jain, D., & Bar-Shalom, D. (2014). Alginate drug delivery systems: Application in context of pharmaceutical and biomedical research. Drug Development and Industrial Pharmacy, 40(12), 1576–1584.
- Javvaji, V., Baradwaj, A. G., Payne, G. F., & Raghavan, S. R. (2011). Light-Activated Ionic Gelation of Common Biopolymers. Langmuir, 27, 12591–12596.
- Langer, R., & Vacanti, J. P. (1993). Tissue Engineering. Science, 260(5110), 920–926.
- Lee, K. Y., & Mooney, D. J. (2012). Alginate: Properties and biomedical applications, Progress in Polymer Science, 37(1), 106–126.
- Li, Y., Rodrigues, J., & Thomás, H. (2012). Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications. Chemical Society Reviews, 41, 2193–2221.
- Lin, H. R., & Yeh, Y. J. (2004). Porous alginate/hydroxyapatite composite scaffolds for bone tissue engineering: preparation, characterization, and in vitro studies. Journal of Biomedical Materials Research Part B: Applied Biomaterials, 71(1), 52–65.
- Martinsen, A., Skjåk-Bræk, G., & Smidsrød, O. (1989). Alginate as Immobilization Material:
- Correlation between Chemical and Physical Properties of Alginate Gel Beads. Biotechnology and Bioengineering, 33, 79–89.
- Ratner, B. D., & Bryant, S. J. (2004). Biomaterials: Where we have been and where we are going. Annual Review of Biomedical Engineering, 6, 41–75.
- Rinuado, M. (2014). Biomaterials based on a natural polysaccharide: Alginate, TIP, 17(1), 92–96.
- Tønnesen, H. H., & Karlsen, J. (2002). Alginate in drug delivery systems. Drug Development and Industrial Pharmacy, 28(6), 621–630.
- Venkatesan, J., Nithya, R., Sudha, P. N., & Kim, S. K. (2014). Role of alginate in bone tissue engineering. Advances in Food and Nutrition Research, 73, 45–57.
- Yotsuyanagi, T., Ohkubo, T., Ohhashi, T., & Ikeda, K. (1987). Calcium-induced gelation of alginic acid and pH-sensitive reswelling of dried gels. Chemical and Pharmaceutical Bulletin, 35(4), 1555–1563.