3rd International Conference on Chemo and BioInformatics, Kragujevac, September 25-26. 2025. (pp. 368-371)
АУТОР(И) / AUTHOR(S): Aleksandar Milovanović, Velibor Isailović, Igor Saveljić, Nenad Filipović
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DOI: 10.46793/ICCBIKG25.368M
САЖЕТАК / ABSTRACT:
Energy loss in stenotic coronary arteries significantly affects blood flow efficiency and contributes to the development of ischemic heart disease. Various methods are employed to diagnose coronary artery stenosis and assess its functional significance, among which Fractional Flow Reserve (FFR) plays a key role. FFR quantifies the pressure drop caused by a stenosis in a coronary artery. Numerous studies have shown that the pressure drop due to diffusion constitutes the dominant component of total pressure loss in coronary stenosis, highlighting the importance of its reliable quantification. This paper presents an enhanced method for calculating the diffusive pressure drop, validated through the studies reported in [1] and [2].
КЉУЧНЕ РЕЧИ / KEYWORDS:
coronary artery stenosis, fractional flow reserve, pressure drop, inertion, diffusion
ПРОЈЕКАТ / ACKNOWLEDGEMENT:
This research is funded by the Ministry of Education and Ministry of Science, Technological Development and Innovation, Republic of Serbia, Grants: 451-03-65/2024- 03/200107 (Faculty of Engineering, University of Kragujevac).
ЛИТЕРАТУРА / REFERENCES:
- A. Milovanovic, V. Isailovic, I. Saveljic, N. Filipovic., Accuracy of Analytically Determined FFR Derived from Coronary Angiography for Non-Invasive Assessment of Coronary Artery Stenosis. Technology and Health Care, 32(6) (2024) 4613-4626.
- A. Milovanović., Analytical and Numerical Modeling of Fractional Flow Reserve in Coronary Arteries, Ph.D. dissertation (in Serbian), Faculty of Engineering, University of Kragujevac (2025) 127 pages.
- G. Mensah, V. Fuster, G. Roth., A Heart-Healthy and Stroke-Free World: Using Data to Inform Global Action, JACC, 82(25) (2023) 2343–2349.
- C. M. Stoney, P.G. Kaufmann, S.M. Czajkowsk., Cardiovascular disease: Psychological, social, and behavioral influences: Introduction to the special issue. American Psychologist, 73(8) (2018) 949-954.
- Y. Huo, M. Svenson, J.S. Choy et all., A validated predictive model of coronary fractional flow reserve. Journal of the Royal Society Interface, 9 (2012) 1325-1338.