1st International Symposium On Biotechnology (2023),  [181-188]

AUTHOR(S) / АУТОР(И): Vladimir Kurćubić, Slaviša Stajić, Nemanja Miletić, Marko Petković


Download Full Pdf   

DOI: 10.46793/SBT28.181K


In an indirect way, through animal nutrition or selection, we can influence the composition and quality of muscle and fat tissue, and thus the nutritional and functional value of meat. The process is longer and is not fully controlled yet. Direct processes improve nutritional properties by adding components with functional properties and/or reducing or removing ingredients that may negatively affect health. Herbal raw materials and extracts, by-products and wastes from fruit and vegetable processing can modify feed in order to achieve a stable health status and preserve animal well-being and sensory quality of meat, with an extended shelf life.


herbal extracts, antimicrobial activity, animal health, fodder, meat quality


  • Álvarez-Martínez F.J., Barrajón-Catalán E., Herranz-López M., Micol V. (2021). Antibacterial plant compounds, extracts and essential oils: An updated review on their effects and putative mechanisms of action. Phytomedicine 90: 153626.
  • Brault S.A., Hannon S.J., Gow S.P., Warr B.N, Withell J., Song J., Williams C.M., Otto S.J.G., Booker C.W., Morley P.S. (2019). Antimicrobial Use on 36 Beef Feedlots in Western Canada: 2008-2012. Frontiers in Veterinary Science 6, 329.
  • Ceruso M., Clement J.A., Todd M.J., Zhang F., Huang Z., Anastasio A., Pepe T., Liu Y. (2020). The Inhibitory Effect of Plant Extracts on Growth of the Foodborne Pathogen, Listeria monocytogenes. Antibiotics 9, 319.
  • Chen Z., Xie Y., Luo J., Chen T., Xi Q., Zhang Y., Sun J. (2021). Dietary supplementation with Moringa oleifera and mulberry leaf affects pork quality from finishing pigs. Journal of Animal Physiology and Animal Nutrition 105(1), 72-79.
  • Dávila-Ramírez J.L., Munguía-Acosta L.L., Morales-Coronado J.G., García-Salinas A.D., González-Ríos H., Celaya-Michel H., Sosa-Castañeda J., Sánchez-Villalba E., Anaya-Islas J., Barrera-Silva M.A. (2020). Addition of a mixture of plant extracts to diets for growing-finishing pigs on growth performance, blood metabolites, carcass traits, organ weight as a percentage of live weight, quality and sensorial analysis of meat. Animals 10(7), 1229.
  • EFSA FEEDAP Panel (EFSA Panel on Additives and Products or Substances used in Animal Feed), Bampidis V., Azimonti G., Bastos M.L., Christensen H., Kouba M., Kos Durjava M., Lopez-Alonso M., Lopez Puente S., Marcon F., Mayo B., Pechová А., Petkova M., Ramos F., Sanz Y., Villa R.E., Woutersen R., Brantom P., Chesson A., Westendorf J., Gregoretti L., Manini P., Dusemund B. (2020): Scientific Opinion on the safety and efficacy of a dried aqueous ethanol extract of Melissa officinalis L. leaves when used as a sensory additive for all animal species. EFSA Journal 18(2), 6016, 17.
  • Ives S.E., Richeson J. (2015). Use of antimicrobial metaphylaxis for the control of bovine respiratory disease in high-risk cattle. Veterinary Clinics: Food Animal Practice 31, 341-350.
  • Karásková K., Suchý P., Straková E. (2015). Current use of phytogenic feed additives in animal nutrition: a review. Czech Journal of Animal Science 60(12), 521-530.
  • Kurćubić V., Stajić S., Miletić N., Stanišić N. (2022). Healthier food is fashionable – consumers love fashion. Applied Sciences 12(19), 10129.
  • Kurćubić, V., Mašković, P., Petrović, T., Lazić, S., Đukić, D., Ilić, Z., Đoković, R., Petrović, M. (2019). Antiviral activity in vitro of five selected indigenous plants against bovine herpes virus-1 (BHV-1) and bovine viral diarrhoea virus (BVDV). Published in 1st International Symposium: Modern Trends in Agricultural Production and Environmental Protection, pp. 419-430. July 02-05. 2019, Tivat-Montenegro: The Balkans Scientific Center of the Russian Academy of Natural Sciences. ISBN 978-86-6042-008-6.
  • Kurćubić, V.S., Mašković, P.Z., Vesković-Moračanin, S.M., Turbatović, L.R., Dodić, A. (2013): Application of Kitaibelia vitifolia extract as antibacterials for decontamination of beef surface. Published in Proceedings in XVIII on biotechnology with international participation, 18(20): 495-503. 15-16. March 2013, Čačak, Faculty of Agriculture in Čačak.
  • Lhermie G., Verteramo C.L., Kaniyamattam K., Tauer L.W., Scott H.M., Gröhn Y.T. (2019). Antimicrobial Policies in United States Beef Production: Choosing the Right Instruments to Reduce Antimicrobial Use and Resistance Under Structural and Market Constraints. Frontiers in Veterinary Science 6, 245.
  • Pandey A.K., Kumar P., Saxena M. J. (2019). Feed Additives in Animal Health. In: Gupta, R., Srivastava, A., Lall, R. (eds.) Nutraceuticals in Veterinary Medicine. Springer, Cham. Available:
  • Rajamanickam K., Yang J., Sakharkar M.K. (2019). Gallic Acid Potentiates the Antimicrobial Activity of Tulathromycin Against Two Key Bovine Respiratory Disease (BRD) Causing-Pathogens. Frontiers in Pharmacology 9:1486.
  • Sharma H., Rai A.K., Dahiya D., Chettri R., Nigam P.S. (2021). Exploring endophytes for in vitro synthesis of bioactive compounds similar to metabolites produced in vivo by plants. AIMS Microbiology 7(2), 175-199.
  • Song L., Hu X., Ren X., Liu J., Liu X. (2022). Antibacterial Modes of Herbal Flavonoids Combat Resistant Bacteria. Frontiers in Pharmacology 13, 873374.
  • WHO (2017). WHO Guidelines on Use of Medically Important Antimicrobials in Food-Producing Animals, Geneva: World Health Organization.
  • Xu M., Chen X., Huang Z., Chen D., Li M., He J., Chen H., Zheng P., Yu J., Luo Y., Yu B. (2022). Effects of dietary grape seed proanthocyanidin extract supplementation on meat quality, muscle fiber characteristics and antioxidant capacity of finishing pigs. Food Chemistry 367, 130781.
  • Yılmaz S., Ergün S., Yiğit M., Yılmaz E. (2022). An Extensive Review on the Use of Feed Additives against Fish Diseases and Improvement of Health Status of Fish in Turkish Aquaculture Sector. Aquaculture Studies 22(3), AQUAST710. QUAST710
  • Zhang D., Ivane N.M.A., Haruna S.A., Zekrumah M., Elysé F.K.R., Tahir H.E., Wang G, Wang C., Zou X. (2022). Recent trends in the micro-encapsulation of plant-derived compounds and their specific application in meat as antioxidants and antimicrobials. Meat Science 191, 108842.