ANTIBIOTIC USE IN DAIRY FARMING: IMPLICATIONS FOR ENVIRONMENTAL SUSTAINABILITY AND RESISTANCE MITIGATION

Climate changes and ecological sustainability in agriculture and food production in Serbia, the region and Southeastern Europe : proceedings, (pp. 370-376)

AUTHOR(S) / АУТОР(И): Boris Ljubojević1, Zvonimir Steiner2, Vesna Gantner2

1Hrvatske šume d.o.o., Zagreb, Croatia; 2Josip Juraj Strossmayer University of Osijek, Faculty of Agrobiotechnical Sciences, Osijek, Croatia

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DOI: 10.46793/MAK2025.370LJ

ABSTRACT / САЖЕТАК:

Antibiotics are essential in dairy farming but contribute to antimicrobial resistance (AMR) and environmental contamination. This review explores antibiotic use practices, impacts on AMR and ecosystems, and strategies such as selective dry cow therapy (SDCT), non-antibiotic alternatives, and improved management. Emphasizing the „One Health“ approach, it highlights sustainable pathways to reduce antibiotic dependency while safeguarding animal health, productivity, and the environment.

KEYWORDS / КЉУЧНЕ РЕЧИ:

Antibiotic use, Antimicrobial resistance, Dairy farming, Environmental impact, Sustainable agriculture

REFERENCES / ЛИТЕРАТУРА:

  • Bennani, H., Mateus, A., Mays, N., Eastmure, E., Stärk, K.D.C., Häsler, B. (2020). Overview of Evidence of Antimicrobial Use and Antimicrobial Resistance in the Food Chain. Antibiotics, 9(2), 49. doi.org/10.3390/antibiotics9020049
  • Bonsaglia, E.C.R., Gomes, M.S., Canisso, I.F., Zhou, Z., Lima, S.F., Rall, V.L.M., Oikonomou, G., Bicalho, R.C., Lima, F.S. (2017). Milk microbiome and bacterial load following dry cow therapy without antibiotics in dairy cows with healthy mammary gland. Scientific reports, 7(1), 8067. doi.org/10.1038/s41598-017-08790-5
  • Bucher, B., Bleul, U. (2019). Die Auswirkung des selektiven Trockenstellens auf die Eutergesundheit in Schweizer Milchviehbetrieben [The Effect of Selective Dry Cow Treatment on the Udder Health in Swiss Dairy Farms]. Schweizer Archiv fur Tierheilkunde, 161(9), 533–544. doi.org/10.17236/sat00219
  • Casseri, E., Bulut, E., Llanos Soto, S., Wemette, M., Stout, A., Greiner Safi, A., Lynch, R., Moroni, P., Ivanek, R. (2022). Understanding Antibiotic Resistance as a Perceived Threat towards Dairy Cattle through Beliefs and Practices: A Survey-Based Study of Dairy Farmers. Antibiotics (Basel, Switzerland), 11(8), 997. doi.org/10.3390/antibiotics11080997
  • Centers for Disease Control and Prevention. (n.d.). One Health basics. U.S. Department of Health and Human Services. Retrieved December 23, 2024, www.cdc.gov/one-health/about/index.html
  • Christaki, E., Marcou, M., Tofarides, A. (2020). Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence. Journal of molecular evolution, 88(1), 26-40. doi.org/10.1007/s00239-019-09914-3
  • Davies, J., Davies, D. (2010). Origins and evolution of antibiotic resistance. Microbiology and molecular biology reviews: MMBR, 74(3), 417–433. doi.org/10.1128/MMBR.00016-10
  • Ferroni, L., Lovito, C., Scoccia, E., Dalmonte, G., Sargenti, M., Pezzotti, G., Maresca, C., Forte, C., Magistrali, C.F. (2020). Antibiotic Consumption on Dairy and Beef Cattle Farms of Central Italy Based on Paper Registers. Antibiotics (Basel, Switzerland), 9(5), 273. doi.org/10.3390/antibiotics9050273
  • Gerber, M., Dürr, S., Bodmer, M. (2021). Reducing Antimicrobial Use by Implementing Evidence-Based, Management-Related Prevention Strategies in Dairy Cows in Switzerland. Frontiers in veterinary science, 7, 611682. doi.org/10.3389/fvets.2020.611682
  • Kupczyński, R., Bednarski, M., Sokołowski, M., Kowalkowski, W., Pacyga, K. (2024). Comparison of Antibiotic Use and the Frequency of Diseases Depending on the Size of Herd and the Type of Cattle Breeding. Animals, 14(13), 1889. doi.org/10.3390/ani14131889
  • Lam, T.J.G.M., Heuvelink, A.E., Gonggrijp, M.A., Santman-Berends, I.M.G.A. (2020). Antimicrobial use in dairy cattle in the Netherlands. Journal of animal science, 98, (Suppl 1), S9–S14. doi.org/10.1093/jas/skaa143
  • Li, X., Xu, C., Liang, B., Kastelic, J.P., Han, B., Tong, X., Gao, J. (2023). Alternatives to antibiotics for treatment of mastitis in dairy cows. Frontiers in veterinary science, 10, 1160350. doi.org/10.3389/fvets.2023.1160350
  • Llanos-Soto, S.G., Vezeau, N., Wemette, M., Bulut, E., Greiner Safi, A., Moroni, P., Shapiro, M. A., Ivanek, R. (2021). Survey of perceptions and attitudes of an international group of veterinarians regarding antibiotic use and resistance on dairy cattle farms. Preventive veterinary medicine, 188, 105253. doi.org/10.1016/j.prevetmed.2020.105253
  • Rajala-Schultz, P., Nødtvedt, A., Halasa, T., Persson Waller, K. (2021). Prudent Use of Antibiotics in Dairy Cows: The Nordic Approach to Udder Health. Frontiers in veterinary science, 8, 623998. doi.org/10.3389/fvets.2021.623998
  • Rowe, S., Kabera, F., Dufour, S., Godden, S., Roy, J.P., Nydam, D. (2023). Selective dry-cow therapy can be implemented successfully in cows of all milk production levels. Journal of dairy science, 106(3), 1953–1967. doi.org/10.3168/jds.2022-22547
  • Saini, V., McClure, J.T., Léger, D., Keefe, G.P., Scholl, D.T., Morck, D.W., Barkema, H.W. (2012). Antimicrobial resistance profiles of common mastitis pathogens on Canadian dairy farms. Journal of dairy science, 95(8), 4319–4332. doi.org/10.3168/jds.2012-5373
  • Suzuki, Y., Hiroki, H., Xie, H., Nishiyama, M., Sakamoto, S.H., Uemura, R., Nukazawa, K., Ogura, Y., Watanabe, T., Kobayashi, I. (2022). Antibiotic-resistant Escherichia coli isolated from dairy cows and their surrounding environment on a livestock farm practicing prudent antimicrobial use. International journal of hygiene and environmental health, 240, 113930. doi.org/10.1016/j.ijheh.2022.113930
  • Tomanić, D., Samardžija, M., Kovačević, Z. (2023). Alternatives to antimicrobial treatment in bovine mastitis therapy: A Review. Antibiotics, 12(4), 683. doi.org/10.3390/antibiotics12040683
  • Virto, M., Santamarina-García, G., Amores, G., Hernández, I. (2022). Antibiotics in Dairy Production: Where Is the Problem? Dairy, 3(3), 541-564. doi.org/10.3390/dairy3030039
  • Wichmann, F., Udikovic-Kolic, N., Andrew, S., Handelsman, J. (2014). Diverse antibiotic resistance genes in dairy cow manure. mBio, 5(2), e01017. doi.org/10.1128/mBio.01017-13