1st International Conference on Chemo and BioInformatics, ICCBIKG 2021, (395-398)
AUTHOR(S) / AUTOR(I): Nikola Z. Srećković, Jelena S. Katanić Stanković, Vladimir B. Mihailović
E-ADRESS / E-ADRESA: nikola.sreckovic@pmf.kg.ac.rs, vladimir.mihailovic@pmf.kg.ac.rs, jkatanic@kg.ac.rs
DOI: 10.46793/ICCBI21.395S
ABSTRACT / SAŽETAK:
Lysimachia vulgaris L., also known as yellow loosestrife, is an herbaceous perennial flowering plant from the family Primulaceae. Traditionally, L. vulgaris has been commonly used in Chinese medicine to increase urination, reduce fever, and treat sexually transmitted ailments. This study aimed to investigate phenolic content, antioxidant activity, and antimicrobial potential of L. vulgaris aerial part (LVA) and root (LVR) methanol extracts. Based on the spectrophotometric determination, both extracts possessed a high level of phenolic compounds. The content of total phenolic compounds (130.14 mg GAE/g) and condensed tannins (120.58 mg GAE/g) was higher in LVR, while total flavonoid (206.93 mg QUE/g) and flavanol (17.02 RUE/g) contents were higher in LVA. DPPH and ABTS assays were used to estimate the antioxidant activity of the extracts, whereby LVR showed better antioxidant potential in both applied methods. The extracts inhibited the growth of most of the tested bacterial and fungal strains with minimal inhibitory concentration values (MICs) ranged between (˂ 0.3125 to 20 mg/mL), whereby the significantly higher antimicrobial activity of LVR was observed. Based on the obtained results, the significant antioxidant and antimicrobial activity of L. vulgaris root extract may be a basis for its further research and potential application in the pharmaceutical and food industry.
KEY WORDS / KLJUČNE REČI:
Lysimachia vulgaris L., Phenolic content, Antioxidant activity, Antimicrobial activity
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