1st International Conference on Chemo and BioInformatics, ICCBIKG 2021, (395-398)
AUTHOR(S) / АУТОР(И): Nikola Z. Srećković, Jelena S. Katanić Stanković, Vladimir B. Mihailović
E-ADRESS / Е-АДРЕСА: firstname.lastname@example.org, email@example.com, firstname.lastname@example.org
ABSTRACT / САЖЕТАК:
Lysimachia vulgaris L., also known as yellow loosestrife, is an herbaceous perennial flowering plant from the family Primulaceae. Traditionally, L. vulgaris has been commonly used in Chinese medicine to increase urination, reduce fever, and treat sexually transmitted ailments. This study aimed to investigate phenolic content, antioxidant activity, and antimicrobial potential of L. vulgaris aerial part (LVA) and root (LVR) methanol extracts. Based on the spectrophotometric determination, both extracts possessed a high level of phenolic compounds. The content of total phenolic compounds (130.14 mg GAE/g) and condensed tannins (120.58 mg GAE/g) was higher in LVR, while total flavonoid (206.93 mg QUE/g) and flavanol (17.02 RUE/g) contents were higher in LVA. DPPH and ABTS assays were used to estimate the antioxidant activity of the extracts, whereby LVR showed better antioxidant potential in both applied methods. The extracts inhibited the growth of most of the tested bacterial and fungal strains with minimal inhibitory concentration values (MICs) ranged between (˂ 0.3125 to 20 mg/mL), whereby the significantly higher antimicrobial activity of LVR was observed. Based on the obtained results, the significant antioxidant and antimicrobial activity of L. vulgaris root extract may be a basis for its further research and potential application in the pharmaceutical and food industry.
KEY WORDS / КЉУЧНЕ РЕЧИ:
Lysimachia vulgaris L., Phenolic content, Antioxidant activity, Antimicrobial activity
REFERENCES / ЛИТЕРАТУРА:
- I. Podolak, P. Koczurkiewicz, M. Michalik, A. Galanty, P. Zajdel, Z. Janeczko, A new cytotoxic triterpene saponin from Lysimachia nummularia L., Carbohydrate Research, 375 (2013) 16-20.
- I. Podolak, P. Koczurkiewicz, A. Galanty, M. Michalik, Cytotoxic triterpene saponins from the underground parts of six Lysimachia L. species, Biochemical Systematics and Ecology, 47 (2013) 116-120.
- D. Winston, Herbal and Nutritional Treatment of Kidney Stones, (n.d.). www.americanherbalistsguild.com. (2021).
- A. Dalar, M. Mukemre, M. Ünal, F. Özgökçe, Traditional Medicinal Plants of Ağrı Province, Turkey, Journal of Ethnopharmacology, 226 (2018) 56-72.
- N. Srećković, J.S. Katanić Stanković, S. Matić, N.R. Mihailović, P. Imbimbo, D.M. Monti, V. Mihailović, Lythrum salicaria L. (Lythraceae) as a promising source of phenolic compounds in the modulation of oxidative stress: Comparison between aerial parts and root extracts, Ind. Crops Prod. 155 (2020) 112781.