HOMEORETSKA REGULACUJA METABOLIČKIH FUNKCIJA KOD KRAVA U PERIPARTALNOM PERIODU

Savetovanje o biotehnologiji sa međunarodnim učešćem (Čačak: 26 ; 2021) (str. 235-243) 
 

АУТОР(И): Radojica Đoković, Marko Cincović, Vladimir Kurćubić, Milun D. Petrović, Miloš Ži. Petrović, Ljiljana Anđušić, Biljana Anđelić

Е-АДРЕСА:

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DOI: 10.46793/SBT26.235DJ

САЖЕТАК:

Cilj ovog rada je da se opišu složeni homeoretski i homeostatski mehanizmi kod mlečnih krava tokom peripartalnog perioda. U regulisanju adaptacije metabolizma tokom peripartalnog perioda, ključnu funkciju ima endokrini sistem. Homeoreza predstavlja funkcionisanje endokrinog sistema i metabolizma u uslovima kada organizam primarno mora da obezbedi određene fiziološke procese, kao što su rast ploda ili laktacija. Tada dolazi do prilagođavanja funkcije svih tkiva na novonastalu situaciju. Homeoretski hormoni (hormon rasta, prolaktin, glukokortikosteroidi, hormoni štitaste žlezde, insulin, glukagon i leptin) kod mlečnih krava u peripartalnom periodu imaju ključnu ulogu u održavanju visoke laktacije i očuvanju zdravlja krava.

КЉУЧНЕ РЕЧИ:

krave, hormoni, metabolizam, peripartalni period

ЛИТЕРАТУРА:

Aceves C., Ruiz A., Romero C., Valverde C., (1985): Homeorhesis during early lactation. Euthyroid sick-like syndrome in lactating cows, Acta Endocrinologia (Copenh), Vol.110, No.4, pp.505-509.

Ahima R.S., Flier J.S. (2000): Leptin, Annual Review of Physiology Vol.62, pp.413-437.

Akers R.M., Bauman D.E., Capuco A.V., Goodman G.T., Tucker H.A., (1981): Prolactin regulation of milk secretion and biochemical differentiation of mammary epithelial cells in periparturient cows. Endocrinology Vol. 109, pp. 23-30.

Asuncion de la G., Devesa J.A., Vina J.R., Barber T. (1994): Hepatic amino acid uptake in the lactating rat: studies in vivo and in vitro. Journal of Nutrition, Vol. 124, p. 2163.

Bauman E., Currie W. (1980): Partitioning of nutriens during pregnacy and lactation. A review of mechanisms involving homeostasis and homeorhesis, Journal of Dairy Science, Vol. 63, pp. 1514-1518.

Bauman D.E., Vernon R.G., (1993): Effects of exogenous bovine somatotropin on lactation, Annual  Review of   Nutrition Vol.13, pp. 437–461.

Bell W. A. (1995): Regulation of organic nutrient metabolism during transition from late pregnancy to early lactation. Journal of Animal Science, Volume 73, Issue 9, pp 2804–2819, https://doi.org/10.2527/1995.7392804x

Bonczek R.R.,Young C.W., Wheaton J.E., Miller K.P. (1988): Responses  of somatotropin, insulin, prolactin and thyroxine to secretion for milk yield in holsteins. Journal of  Dairy science, Vol. 71, pp. 2470.

Bornstein S.R., Uhlmann K., Haidan A., Ehrhart-Bornstein M., Scherbaum W. A. (1997): Evidence for a novel peripheral action of leptin as a metabolic signal to the adrenal gland. Diabetes, Vol. 46, pp. 1235-1238.

Bloom K, Halse K, (1975): Corticoids in nuctural blood plasma of cows in the field related to stage of lactation and plasma aceto-acetat. Journal of Dairy Science, Vol. 8, pp. 1170-1174.

Butler S.T., Marr A.L., Pelton S.H., Radcliff R.P., Lucy M.C., Butler W.R. (2003): Insulin restores GH responsiveness during lactation-induced negative energy balance in dairy cattle: Effects on expression of IGF-I and GH receptor 1A. J Endocrinology, Vol. 176, pp. 205–217.

Considine R.V. (2003): Endocrine regulation of leptin production. In: Henson MC, Castracane VD, editors. Leptin and reproduction. New York: Kluwer Academic/Plenum Publishers, 39-52.

De Boer G., Trenkle A., Young J. W. (1985): Glucagon, insulin, growth hormone and some blood metabolites during either feed restriction, ketonemia of lactating cows. Journal of Dairy Science, Vol. 68, pp. 326-329.

Cherrington A.D., Liqenquist J.E., (1981): Role of glucagon in regulating glucose production in vivo. Pages 221-253 in Glucagon: Physiology, Pathophysiology, and morphology of the pancreatic A Cells. Current Endo-crinology. R. H. Unger and L. Orci, ed. Elsevier, New York.

Drackley J.K. (1999): Biology of dairy cows during the transition period: the final frontier? J Dairy Sci, Vol.82, pp. 2269-2273.

Drackley J.K., Overton T.R., Douglas G.N. (2001): Adaptations of glucose and long-chain fatty acid metabolism in liver of dairy cows during periparturient period, J Dairy Sci, Vol.84, pp.(E suppl.) E 100 – E 112.

Đoković R., Šamanc H., Bošković-Bogosavljević S. (2000): Triiodothyronine, thyroxine, free fatty acids and triglyceride concentrations in blood and fat liver contenet in post parturient dairy cows. Book of abstracts of the 51st Annual Meeting of the European Association for Animal Production, The Hague, The Netherlands.

Đoković R., Šamanc H., Bošković-Bogosavljević S., Petrović M., Dosković V., Rajičić V.(2002): Koncentracije lipida, glukoze i insulina u krvi i stepeni zamašćenja jetre kod zdravih i ketoznih krava. Biotechnology in animal husbandry, Vol. 18, 5-6, str. 177-184, Beograd-Zemun.

Đoković R., Šamanc H., Bošković-Bogosavljević S. (2003): Koncentracije slobodnih masnih kiselina, glukoze i insulina u krvi kod visoko-produktivnih mlečnih krava i peripartalnom periodu. Veterinarski glasnik, Vol. 57, 7-8, str. 405-423, Beograd.

Đoković R., Šamanc H., Jovanović M., Nikolić Z. (2007): Blood concentrations of thyroid hormones and lipids and content of lipids in the liver in dairy cows in transitional period. Acta Veterinaria Brno, Vol. 76, pp. 525-532.

Đoković (2010): Endokrini status mlečnih krava. Monografija. Agronomski fakultet, Čačak.

Đokovic R., Cincovic M., Belic B., Toholj B., Davidov I., Hristovska T. (2015): Relationship between blood metabolic hormones, metabolites and energy balance in Simmental dairy cows during peripartum period and lactation. Pakistan Veterinary Journal, Vol.35, pp. 163-167.

Gvozdić D. (2005): Uloga hormona u regulisanju prometa energije u peripartalnom periodu, Zbornik radova, Etiopatogeneza i dijagnostika poremećaja metabolizma i reprodukcije goveda, 4. Simpozijum – Ishrana, reprodukcija i zaštita zdravlja goveda, 27.9 – 1.10, str.103-125, Subotica.

Jones J.I., Clemmons D.R. (1995): Insulin-like growth factors and their binding proteins: biological actions. Endocrine Reviews, Vol.16, pp. 3-34.

Juergens W.G., Stockdale F.E., Topper Y.J., Elias J.J., (1965): Hormone-dependent differentiation of mammary gland in vitro. Proc Natl Acad Sci, Vol. 54, pp. 629-634.

Hart I.C., Bines J.A., Roy J., Morant S. (1978): Plasma thyroxine index in high and low-yielding cattle and in calves of different breeds. Journal of  Endocrinology, Vol. 80, p. 52.

Kahl S., Capuco A.V., Binelli M., Vanderkooi W.K., Tucker H.A., Moseley W.M,. (1995): Comparison of growth hormone-releasing factor and somatotropin: thyroid status of lactating, primiparous cows. Journal of Dairy Science. Vol. 78, No.10, pp. 2150-2158.

Koprowski J.A., Tucker H.A., (1973): Serum prolactin during various physiological states and its relationship to milk production in the bovine. Endocrinology, Vol. 92, pp. 1480-1487.

  1. Kulcsár, Sz. Jánosi, T. Lehtolainen, L. Kátai, C. Delavaud, O. Balogh, Y. Chilliard, S. Pyöräläc, P. Rudas, Gy. Huszenicza (2005): Feeding-unrelated factors influencing the plasma leptin level in ruminants. Domestic Animal Endocrinology. Vol 29, Issue 1, Pages 214-226.

Sartin J.L., Kemppainnen R.J., Cummins K.A., Williams J.C. (1988): Plasma concentrations of metabolic hormones in high and low producting dairy cows. Journal of Dairy Science, Vol. 71, pp. 650-657.

Smith G., Hansel W., Coppock C. (1976): Plasma growth hormone and insulin during early lactation in cows fed silage based diets. Journal of Dairy Science Vol. 59, pp. 135-140.

Šamanc H., Damnjanović Z., Nikolić J.A., Radojčić B., Anđelković M., Lekić N. (1993): Endokrina regulacija metaboličkih procesa kod krava u graviditetu i laktaciji, Veterinarski glasnik, No.4-5, str.319-327.

Šamanc H., Sinovec Z., Cornescu H., (2005): Osnovi poremećaja prometa energije visoko-mlečnih krava, Zbornik radova, Etiopatogeneza i dijagnostika poremećaja metabolizma i reprodukcije goveda, 4. Simpozijum – Ishrana, reprodukcija i zaštita zdravlja goveda, 27.9 – 1.10, str. 89-103, Subotica.

Vicini J.L., Buonomo F.O., Veenhuizen J.J., Miller M.A., Clemmons D.R., Collier R.J. (1991): Nutrient balance and stage of lactation affect responses of insulin, insulin-like growth factors-l and II, and insulin-like growth factor-binding protein 2 to somatotropin administration in dairy cows. Journal of Nutrition, Vol.121, pp.1656-1664.