Savetovanje o biotehnologiji sa međunarodnim učešćem (Čačak: 27; 2022) (str. 489-495)

АУТОР(И): Neda Pavlović, Jelena Mijalković, Verica Đorđević, Branko Bugarski, Zorica Knežević Jugović


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DOI: 10.46793/SBT27.489P


Liposomes have been researched as carriers for encapsulation of bioactive protein hydrolysate, despite low stability which makes them difficult to use. Using cholesterol or octadecylamine as lipid membrane stabilizers, soy protein hydrolysate is effectively encapsulated in liposomes created with phospholipon. Presence of both stabilizers concurrently resulted the highest efficiency 49.7%, while increasing the phospholipon mass had no effect. Particle size was raised (265 to 335 nm) as a result of the octadecylamine addition, and zeta potential was positive (36.7 mV), as compared to the cholesterol addition (-25.1 mV). Liposomes enabled extended hydrolysate release with retained its bioactivity.


soy protein hydrolysate, liposomes, octadecylamine, antioxidant activity, controlled release


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