AUTHOR(S) / АУТОР(И): Katarina Đorđević, Božidar Pindović, Katarina Mihajlović, Jelena Terzić, Zorka Stanić, Katarina Postolović, Vladimir Živković, Vladimir Jakovljević, Tamara Nikolić Turnić
DOI: 10.46793/SBT30.74KDJ
ABSTRACT / САЖЕТАК:
The aim of this study was to examine the antioxidant capacity of curcumin and whether it modulates RA-induced oxidative stress. Pro-oxidants from plasma and coronary venous effluent were determined spectrophotometrically. The concentration of nitrite was significantly lower in the curcumin treated group compared to the disease group (p < 0.05), while the concentrations of superoxide anion radical, hydrogen peroxide and lipid peroxidation index were lower in curcumin group, but without statistical significance between the groups. Curcumin has a beneficial antioxidant effect in the treatment of RA, but considering that this was a pilot study, additional investigations will be performed.
KEYWORDS / КЉУЧНЕ РЕЧИ:
curcumin, rheumatoid arthritis, oxidative stress
ACKNOWLEDGEMENT / ПРОЈЕКАТ:
This research was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Agreement No. 451-03- 65/2024-03/200111).
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